The Science of Relapse

(with mri scans of the cocaine craving brain with and without baclofen)



Total Running Time: 10:54 min.

In an effort to understand relapse as a part of the addiction disorder, researchers at the University of Pennsylvania enlisted addicts to participate in a study investigating the brain's response to drug cues. One subject, William, is addicted to crack, and describes his relapses as "battles" he can't win. Anna Rose Childress, a neuroscientist, explains that William's brain is being "tricked" by "go" impulses in the brain, and that his urges are triggered by environmental and sensory images. Technology now allows doctors to examine the brain in order to "fix what's broken." Combining medication with behavioral treatment, the brain can now be "reset" to help addicts like William keep addictions under control.

Source: https://www.hbo.com/addiction/thefilm/centerpiece/614_segment_3.html

and on youtube a short version: https://www.youtube.com/watch?v=byain0Vo5mo

















(The experimental medication is baclofen)

see also https://www.djbroadcast.net/article/81497/hallo-baclofen-vaarwel-verslaving

and https://nl.wikipedia.org/wiki/Baclofen for many references on the subject